14 years of technical post
When a cell or host is defined as permissive in virology, it refers to the fact that the virus is able to circumvent host defenses and is able to replicate. Usually this occurs when the virus has modulated one or several of the host cellular intrinsic defenses, and the host immune system. The permissive state of a host has now been determined to be the primary factor in determining whether a virus will cause pathological symptoms in a host.
The significance between the difference of the two has now been elucidated with study of the rabbit-lethal myxoma virus. Many species of rabbit cells in culture (without the presence of any antiviral defenses that would normally be in a host) can be infected by the myxoma virus, causing infection and cell death. However, inoculation of the myxoma virus in many species of rabbit shows that only one species of rabbit is affected, the rest being completely unharmed by the virus (lack of even viral shedding). This has been determined to be a result of…
Microsoft announces new rich Internet applications development and streaming media features; company outlines plans for supporting Windows, Mac and Linux tools for developing Silverlight applications. Microsoft Corp. today announced the…
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